Oh, that dangerous squalene!

Someone was saying that “Squalene” was a dangerous substance that is dangerous to inject. They say that with great sincerity. It’s keeping people from getting their innoculations.

The new strain of virus is likely to replace the older one; and if there’s a third wave later in the year it could be more virulent. We had the equivalent of a flu season’s worth of illness and deaths from August to November, when there are normally very few. In Canada, most of the people who died have been younger women (which is most unusual). So getting your flu shot is important, perhaps vital.

The fear-mongers are totally off-base with fears of squalene. It is one of many fats, or lipids as scientists call them, made in our own bodies. If you’ve ever had olive oil, corn oil, cod-liver oil, or shark-liver oil, meat, or fish, you’ve been drinking and eating squalene. Concentrated squalene from shark-liver oil is sold in health stores for high prices as a beneficial natural substance. We have it in every cell of our bodies. It’s stored in our livers, circulates in our blood, and oozes out of our skin. Injecting a few more milligrams of squalene into a body already awash with the stuff is completely safe.

The adjuvant used with the vaccine is made up of squalene, vitamin E, and water. It emulsifies the vaccine to give it more surface area (lots of little droplets) so that you only need 1/4 of the actual virus protein. The search for something causing Gulf War Syndrome found a tiny amount of squalene, so tiny that researchers think it probably came from the oils in someone’s fingerprint.

Here’s a link to a research paper (PDF), “Measurement of squalene in human tissues and plasma.” This paper mentions that human skin secretes squalene, that our fat contains a lot of squalene, and that our bloodstream contains squalene. It’s in our bile and gallbladders.

Here’s a link to a research paper (PDF), “Measurement of squalene in human tissues and plasma.” This paper mentions that human skin secretes squalene, that our fat contains a lot of squalene, and that our bloodstream contains squalene. It’s in our bile and gallbladders.

The article also says that an American eating a diet of 2000 Calories probably eats about 25 milligrams of squalene. Blood plasma levels in healthy, fasting Americans were about 20 – 70 micrograms per decilitre. They note that getting accurate and consistent measurement of squalene in biological samples, they must clean glassware thoroughly:

PRECAUTIONS: The high rate of secretion of squalene by the human skin leads to gross contamination of laboratory glassware unless exceptional care is taken to render every item squalene-free. Only after some experience is gained with the method is it feasible to not use polyvinyl gloves pre-rinsed with petrol ether. After routine cleaning of glassware, including that in which biologic samples are to be collected, we sonicate [agitate by ultrasound –M.] for 3 min in detergent; then, after rinsing away the detergent in distilled water, we sonicate again in distilled water before air-drying. Then, immediately prior to use of the glassware, it is rinsed in chloroform-methanol 2:1 and then air-dried.

So you see that just touching the inside of a container by accident could result in a false positive for squalene.

The Canadian vaccine contains 3.8 micrograms of viral protein (HA) and 5 micrograms of preservative solution mixed with 12 milligrams of Vitamin E, 11 milligrams of squalene, and 5 milligrams of Polysorbate 80, whatever that is.

The article quoted above notes that a person secretes 125 – 475 milligrams of squalene per day from their skin.

The viral material, haemagglutinin (the H in H1), is made up of cleaned and purified fragments of virus shell, so it can’t give anyone flu. If you get flu after the shot, it’s because you were incubating the virus (and infectious to others) but had not yet developed symptoms.

And this isn’t news: the paper is from 1976, more than 30 years ago. The intention of the paper was to see if researchers could learn to make consistent measurements of squalene in samples.

20 Responses to “Oh, that dangerous squalene!”

  1. bennymay Says:

    Government fights against Pilot:
    a personal story, with a difference
    http://bennymay.wordpress.com/

  2. monado Says:

    Wow, you sound right paranoid! It’s all their fault, is it?

    • bennymay Says:

      Dude, was that directed at me?
      {Paranoia relates to delusions of persecution, unwarranted jealousy, exaggerated self-importance, unjustified suspicion or mistrust of others. The doctors say that is NOT me.
      I have no delusions beyond what the RAAF admits.
      I don’t see myself as overly important.
      I’m relatively trusting.}

      The top medical experts in Australia (in the relevant area) said the air force vaccinations are the most probable cause of the medical condition I began suffering when the air force vaccinated me.
      So, is it their fault?
      Well, read my blog, and decide for yourself.

  3. blogo-links « Coffee and Sci(ence) Says:

    […] Oh, that dangerous squalene!: […]

  4. SusanC Says:

    Let me propose an experiment:

    Take some olive oil, corn oil, cod-liver oil, or shark-liver oil, meat, or fish (or even sebum, the oil on your own skin). Put them through a blender. Sterilize the mixture. Then inject 0.25ml into yourself.

    Volunteers, anyone??

  5. monado Says:

    You’d get a reaction to the foreign proteins of corn, olives, or flesh. However, if you used your own skin’s oil or purified squalene, there would be no reaction.

    Incidentally, we make tiny amounts of our own formaldehyde, too, and the concentration in a vaccine is so low that we’re diluting what’s already in our bloodstreams.

  6. Monado Says:

    Oh, here’s one: Potentiation by squalene of antitumor effect of 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-nitros ourea in a murine tumor system: “The effect of squalene (SQ) on the antitumor activity of 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitros urea (ACNU) was studied in a murine tumor system. SQ at 4.2 g/kg exhibited a significant potentiating effect on the activity of 10 mg/kg of ACNU against lymphocytic leukemia P388 and resulted in some long-term survivors without toxicity to the host. Simultaneous administration of SQ and ACNU was most effective.” Injected squalene makes anti-cancer drug more effective.

  7. Monado Says:

    And here’s a bit on the “injecting squalene is BAD” research. theme:

    … and the evidence refuting the claim anthrax vaccine given to Gulf War vets contained squalene, much less that it is the cause of Gulf War Syndrome (GWS). However, the main claim Dr. Mercola makes here is that squalene, when injected, will trigger an immunologic response and that these squalene-specific antibodies will then cause untold havoc in your body. That’s a testable hypothesis, and don’t you know scientists just love to test hypotheses?

    To support his assertion he cites a small cohort study from 2000 that reported anti-squalene antibodies in veterans afflicted by GWS. Case closed, right? Not so much. A larger and better-designed study found no correlation between the presence of squalene antibodies and symptoms of Gulf War Syndrome. More important regarding vaccine safety, a subsequent study using more sensitive and accurate methods than those used in the study by Asa established that anti-squalene antibodies are present in a large percentage of adults regardless of exposure to squalene from vaccines, and are unchanged by subsequent exposure to squalene containing adjuvants.

    In other words, adjuvants containing squalene don’t induce an immune response to squalene. No antibodies are created to cause whatever autoimmune phenomena Dr. Mercola cares to postulate, including GWS. His hypothesis fails.

    Links from the quote:
    J. Pharm Biomed Analysis 2002: The method has a limit of detection of 140 parts per billion and has been successfully applied to a commercial vaccine known to contain squalene. We have applied this method to 17 lots of Anthrax Vaccine Adsorbed administered to members of the US Armed Forces. No squalene has been detected in any lot. The results of these analyses provide direct evidence for the absence of squalene as an ingredient or a manufacturing contaminant in Anthrax Vaccine Adsorbed.
    J. Pharm Biomed Analysis 2006: Specific lots of anthrax vaccine adsorbed administered to members of the U.S. Armed Forces have been alleged to contain squalene, a chemical purported to be associated with illnesses of Gulf War veterans. A method of enhanced sensitivity for determining squalene in anthrax vaccine adsorbed using high-performance liquid chromatography with photodiode array detection has been developed, validated, and applied to 44 bottles of 38 lots of anthrax vaccine. In 43 bottles of 37 lots, no squalene was detected within a detection limit of 1ng/0.5ml dose (2 parts-per-billion). One lot, FAV008, was found to contain trace amounts of squalene at 7, 9, and 1microgl(-1), levels considerably below normal human plasma levels (290microgl(-1)). The overall results of this investigation provide direct evidence for the absence of squalene in nearly all of anthrax vaccine preparations tested.
    Vaccine. 2009: Since the end of the 1991 Gulf War, there have been reports of unexplained, multisymptom illnesses afflicting veterans who consistently report more symptoms than do nondeployed veterans. One of the many possible exposures suspected of causing chronic multisymptom illnesses Gulf War veterans is squalene, thought to be present in anthrax vaccine. We examined the relationship between squalene antibodies and chronic symptoms reported by Navy construction workers (Seabees), n=579. 30.2% were deployers, 7.4% were defined as ill, and 43.5% were positive for squalene antibodies. We found no association between squalene antibody status and chronic multisymptom illness (p=0.465). The etiology of Gulf War syndrome remains unknown, but should not include squalene antibody status.
    Clinical and Vaccine Immunology, 2006: Squalene is a naturally occurring oil which has been used in the development of vaccine adjuvants, such as the oil-in-water emulsion MF59. In past years, by use of noncontrolled and nonvalidated assays, a claim was made that antisqualene antibodies were detectable in the sera of individuals with the so-called Gulf War syndrome. Using a validated enzyme-linked immunosorbent assay for the quantitation of immunoglobulin G (IgG) and IgM antibodies against squalene, we demonstrated that antisqualene antibodies are frequently detectable at very low titers in the sera of subjects who were never immunized with vaccines containing squalene. More importantly, vaccination with a subunit influenza vaccine with the MF59 adjuvant neither induced antisqualene antibodies nor enhanced preexisting antisqualene antibody titers. In conclusion, antisqualene antibodies are not increased by immunization with vaccines with the MF59 adjuvant. These data extend the safety profile of the MF59 emulsion adjuvant.

  8. Fred Says:

    O.K., Fine Don’t blame Squalene. Do you really think it matters to all the people suffering from autoimmune conditions as a result of the H1N1 Vaccine what exact component caused their suffering? See the link below!

    http://canadiansforhealthfreedom.wordpress.com/h1n1-vaccine-side-effects-canadians-please-report-here/

    Yes there is a lot of Canadains suffering.

    Why don’t you take some of your mental prowess and concern youself with finding the smoking gun, if not Squalene then what?

    You see we that suffer don’t care what caused this, we just want it to stop. We can’t understand why our surffering is being unreconized by the medical comunity and the government we trusted that and so easily took full responsibility for this vacinne.

    Your missing the real issue here, can I make this any clearer for you?

  9. monado Says:

    That’s because as far as real research goes, not “OMG I’ve got an ache it must be teh vaccine,” there are very few side effects and most of them are temporary reactions. Look up the hundreds of phone calls that the BC government got about reactions to aerial spraying, followed by hundreds of embarrassed silences when the callers found out that the spraying hadn’t taken place as scheduled.

  10. Chris Says:

    Hi,
    I’m from the UK & had a H1N1 shot in October 2011.
    Since January 2012 I have had severe hives/urticaria and joint & facial swelling known as angioedema.
    I am awaiting blood test results for autoimmune type antibodies.
    I was obviously intrigued when I read about the flu shot and the alleged autoimmune side effects having not previously linked the shot with my condition but then thinking that the shot could be deemed a significant event.
    The most worrying supposed evidence to support the dangers for me are the reactions in animal lab tests.
    Personally I have never previously had hives and lead a very healthy life style.
    This forum seems to be a place where I have found an almost calm discussion type of atmosphere so I’m hoping someone could shed some light on the animal reactions if they say that injecting squalene is safe for us humans.
    There seems to be no calm discussion on this matter. The strongly and aggressive polarised opinions don’t really help anybody who is worried about this.
    I’m not working for the New World Order and I also don’t really trust those in power but I am having a hard time physically so hopefully this thread isn’t totally dead and I can make some sense of all the ‘evidence’ with your help.
    Thanks,
    Chris

  11. monado Says:

    Hi, Chris. I developed a physical allergy several years ago after being exposed to cold, wet rain. Before that, I developed a localized allergy to detergents after some commecial cleaner got into a scrape. In my experience, allergies accumulate over one’s life. Our immune systems get less active as we age and things flare up, such as shingles from viruses left over by childhood cases of chicken pox. At the same time, we can still trigger autoimmune diseases such as arthritis. We ingest hundreds of thousands of germs every day, not to mention airborne pollutants, heavy metals from car exhausts, and so on. There’s no reason to assume that a vaccine given months before was the cause of your troubles. The available research on vaccine harm doesn’t connect it with anything. The OMG TOXINS reaction started as soon as vaccines were invented and have yet to come up with any proof. I suggest that you discuss your case with a doctor and do research on reputable medical sites such as Medscape and the National Institutes of Health. Good luck!

  12. Sue Says:

    I was interested in reading of the dangers of squalene adjuvants, and the terrible effects it supposedly had on Gulf War vets. Then, in 2009, the adjuvant was introduced into seasonal flu jabs for the elderly, and those at risk. Some pensioners have therefore had 4 vaccinations with the squalene adjuvant, since 2009, and there is hardly a medical catastrophe to be seen! Given that apparently, the concentration of adjuvant is higher in the flu jab than the vaccines the Gulf War vets had, I’m beginning to question if squalene really is the culprit? Surely a yearly vaccination of such a, supposedly dangerous squalene laden vaccine, would have brought on a complete disaster for those who get the jab every year? Any answers will be interesting. Thanks

    • monado Says:

      It’s not a poison: it’s found in foods and your body makes it and uses it on the pathway to making cholesterol, which is a precursor to vital hormones. Your own blood contains sqalene. It is sold as a food supplement in the form of shark’s liver oil. Traces found in vaccines where it is not added appear to come from the oils left by fingerprints on laboratory glassware. The amounts found are far less than the concentration already in human blood.

      The anthrax vaccine given to U.S. soldiers used aluminum hydroxide as an adjuvant. The purpose of an adjuvant is to boost immune response and allow us to use less of the antigen (disease substance that we want to become immune to). The U.S. doesn’t use squalene as an adjuvant in any vaccine. See this Q&A paper from the U.S. Food & Drug Administration (Portable Document Format file).

  13. gabriel Says:

    Monado, your post is missleading, if you read the studies done on the danger of Squalene and the GWS gulf war syndrome problems you would understand that Squalene is not the big danger here, it’s the method of intake=IM Intra muscular, along side the virus, causes the body to treat squalene as a foreign and dangerous substance and our bodies anti-bodies attack squalene injected and in the rest of the body, even the naturally occuring squalene, this causes joint inflamation/Rheumatoid Arthritis and many other diseases….next time do your research before tryign to look smart and talking bs on a public platform.

  14. gabriel Says:

    It’s mostly the fact that it is introduced together with cells of the virus in a non natural way triggers the body to fight it off and the body can’t differentiate between natural and injected squalene so it fights it all off…

  15. monado Says:

    Show me a study that finds squalene injected intramuscularly with a vaccine is treated any differently by the body than the squalene it makes for itself.

  16. peter nikolai Says:

    If the squalene injected with the vaccine as an adjuvant did NOT cause anything different to occur when it was attached to the antivirus molecule, then there would be no reason for it to be included with the vaccine. Therefore – the squalene attached to the antivirus is treated differently than the squalene that is naturally occurring within our bodies, and not attached to antivirus molecules.

    • monado Says:

      The squalene isn’t attached to anything. There is no “antivirus molecule.” You do not know what you are talking about.


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