Heparin shipments from China stopped at U.S. border

Heparin from China is causing allergic reactions and even deaths:heparin logo

Updated Fri. Mar. 14 2008 8:05 PM ET — The Associated Press

WASHINGTON — U.S. health officials have ordered all imports of the blood thinner heparin, and its raw ingredient, stopped at the border for testing to detect a contaminant linked to 19 deaths.

The Food and Drug Administration announced the move Friday, the latest step in its widening investigation of hundreds of allergic-type reactions linked to Baxter International’s heparin injections.

The FDA found the contaminant in 20 of 28 samples of raw heparin that the agency tested from Baxter’s main supplier, a Chinese factory owned by Wisconsin-based Scientific Protein Laboratories.

On March 7, a Health Canada spokeswoman said by e-mail that the products made by Baxter International and associated with the U.S. deaths are not sold in Canada.

A different brand of heparin also has been recalled in Germany after 80 patients there got sick, and the German manufacturer said Friday that it was narrowing the source of contamination to another Chinese supplier.

FDA announced some good news Friday, saying it had learned of no additional deaths and just two more allergic reactions since Baxter recalled the last of the suspect heparin late last month.

Scientists don’t yet know exactly what the contaminant is, except that it mimics heparin so closely that standard drug-purity tests won’t catch it. Nor is it certain that the contaminant is to blame for the allergic reactions, although it is the prime suspect.

But the FDA is “very close” to identifying the substance, a step that should help tell if the contaminant got into heparin by accident or by fraud, said FDA drug chief Dr. Janet Woodcock.

Heparin is derived from pig intestines, and China is the world’s leading supplier. Tiny family-run workshops near slaughterhouses send batches of raw ingredients to larger middlemen before they reach factories like SPL’s in Changzhou. The FDA hasn’t yet inspected those workshops, saying that was something under discussion with Chinese officials.

Two weeks ago, the FDA urged all remaining U.S. heparin manufacturers to start using more sophisticated tests to be sure their products were contaminant-free. Friday, the agency said worldwide testing had begun. ….

Most of the actual import testing will be done by five of the leading heparin manufacturers in the U.S., which will be cleared to sell their products once the FDA receives those test results.

The FDA itself will test any remaining shipments that arrive from abroad.

The FDA wouldn’t name the five companies that will do their own testing, and acknowledged it has no plans to do spot checks of the quality of those companies’ tests.

Because, after all, who needs to watch the watchers?

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Comment on U.S. earthquake safety plan

Harold at Ontario Geofish points out that the U.S. National Institute of Standards and Technology is accepting public comment on a draft plan for mitigating the hazards of earthquakes. NIST says,

Earthquakes can’t be prevented, but their impact on life, property, and the economy can and should be managed, according to the agencies participating in the National Earthquake Hazards Reduction Program, which is working on design and construction techniques for new and existing buildings and also lifelines, monitoring and early-warning systems, coordinated emergency preparedness plans, and public education….

The draft plan lists nine strategic priorities for the next four years, including implementation of the Advanced National Seismic System for impact notification, hazard assessments, and research; development of cost-effective techniques and tools to design new earthquake-resistant buildings and to improve the survivability of existing buildings; creation of realistic earthquake scenarios to help communities and businesses plan for earthquake consequences; and design of earthquake-resilient infrastructure “to end vulnerabilities and possible cascading failures in critical, interconnected transportation, ports, energy , water, sewage, communications and industrial production systems,” according to NIST’s April 15 announcement of the comment period.

Harold wonders if the plan will be implemented, which would take money.

Expelled for immorality and incompetence

Blake Stacey at Science After Sunclipse has a succinct post about the very ironic clash between Expelled the movie and facts.

And so it came to pass that the creationists, realizing that they would be caught ripping off copyrighted material for their propaganda movie, pushed back the release date and did a quick hack job to cover up the stolen footage.

Read more.

This image (from Quidam ) makes the point clearly:

quidamsretort.jpg

That’s Expelled for you.

Aviation weather site

I’ve just found a lovely little online resource, the Aviation Weather site for Canada. You can do practically anything here, including file a flight plan.

NAV Can web site

Obviously there’s a wealth of information, including Volcanic Ash reports. At random, I clicked on “Live RVR,” which brought me to the IIDS page.

Weather IIDS page FIR

There I picked the name of an airport. That gave me the wind speed and ceiling. Theres’e even a neat little graphic map of the airport. This one is Vancouver.

Vancouver aerodrome weather

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